K-Ras-IN-1

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Selleck Chemicals

SKU:S0023-5MG

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K-Ras-IN-1 is an inhibitor of KRAS used in studies of MAPK / ERK Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer, cell cycle, and cell signaling models.

By inhibiting KRAS, K-Ras-IN-1 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. This context is compatible with phosphorylation mapping, pathway-response, and growth assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving KRAS
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer, cell cycle, and cell signaling models

Overall, K-Ras-IN-1 is appropriate when a defined chemical perturbant is needed to connect KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
KRAS
Target Class:
Other
Pathways:
MAPK / ERK Signaling
Research Area:
Cancer • Cell Cycle • Cell Signaling
CAS No.:
84783-01-7
Molecular Weight:
207.29
Formula:
C₁₁H₁₃NOS
SMILES:
C1CCN(C1)C(=S)C2=CC=CC=C2O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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