JAK2 (JTK10) Antibody

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BiCell Scientific

SKU:52712-50UL

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Size
Blocking Peptide
Quantity
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About the Target

Bring JAK2 (JTK10) into view to explore changes across conditions. JAK2 is a signaling node often evaluated by abundance, localization, and modification-dependent states. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol JTK10.

Research Context

Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Consider these angles when interpreting target-level changes:

  • interaction patterns within multi-protein complexes
  • time-resolved changes following stimulation or inhibition
  • condition-to-condition comparisons with matched controls
  • localization shifts between cytoplasm, membrane, and nucleus

Variant Considerations

When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

If your study spans multiple model systems, it can help to define a shared reference condition for JAK2 so cross-sample contrasts stay meaningful.

When interpreting JAK2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

For challenging targets, pairing JAK2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

Select the regular format version to keep JAK2 (JTK10) interpretation aligned with your workflow goals.

Targets:
JAK2
Research Area:
Cell Signaling
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (17-aa) derived from the C-terminal region of mouse JAK2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
O60674
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 76.5% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C