Irsogladine

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Selleck Chemicals

SKU:S1929-50MG

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Irsogladine is an inhibitor of PDE and AChR used in studies of Neurotransmission. In practice, this places the compound in experiments that measure synaptic signaling, receptor activity, and neuronal excitability in cardiovascular, metabolism, and neuroscience models.

By inhibiting PDE and AChR, Irsogladine can be used to examine synaptic signaling, receptor activity, and neuronal excitability. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cardiovascular, metabolism, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PDE and AChR
  • Pathway perturbation studies connected to Neurotransmission
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Irsogladine is appropriate when a defined chemical perturbant is needed to connect PDE and AChR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, metabolism, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PDE • AChR
Target Class:
Enzyme
Pathways:
Neurotransmission
Research Area:
Cardiovascular • Metabolism • Neuroscience
CAS No.:
57381-26-7
Molecular Weight:
256.09
Formula:
C₉H₇Cl₂N₅
SMILES:
C1=CC(=C(C=C1Cl)C2=NC(=NC(=N2)N)N)Cl
InChIKey:
ATCGGEJZONJOCL-UHFFFAOYSA-N
PubChem:
3752
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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