Integrin alpha-X (ITGAX or CD11c) Antibody - Western Blot Validated
BiCell Scientific
SKU:10014-WB-50UL
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About the Target
To connect mechanism with measurement, this antibody lets you evaluate Integrin alpha-X in pathway-driven studies. Integrin alpha-X is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Tracking Integrin alpha-X can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Comparative experiments can separate expression differences from changes in adhesion structure abundance. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- effects of adhesion inhibitors or matrix composition
- remodeling after changes in substrate or mechanical stress
- co-variation with cytoskeletal and scaffold partners
Variant Considerations
If your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing Integrin alpha-X measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For challenging targets, pairing Integrin alpha-X measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
The denaturing-format option supports mechanistic reading of Integrin alpha-X when interactions and context are the focus.
- Targets:
- ITGAX
- Research Area:
- Developmental Biology • Immunology
- Application:
- WB
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal cytoplasmic region of mouse integrin alpha-X protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P20702
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 47.1% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C