Integrin alpha-E (ITGAE or CD103) Antibody - Western Blot Validated

Biological Background

Use this antibody to analyze Integrin alpha-E in your model system. Integrin alpha-E is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol ITGAE.

Use in the Laboratory

Comparative experiments can separate expression differences from changes in adhesion structure abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Interpreting changes can benefit from separating expression differences from redistribution, particularly when the target cycles between compartments.

To keep datasets interpretable, labs often document:

• focal adhesion versus diffuse membrane distribution
• remodeling after changes in substrate or mechanical stress
• effects of adhesion inhibitors or matrix composition
• co-variation with cytoskeletal and scaffold partners

Version Notes

If your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.

For challenging targets, pairing Integrin alpha-E measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

If your study spans multiple model systems, it can help to define a shared reference condition for Integrin alpha-E so cross-sample contrasts stay meaningful.

With a clear focus on Integrin alpha-E, this denaturing-format option fits streamlined studies and fast iteration.