Integrin alpha-3 (ITGA3 or CD49c) Antibody
BiCell Scientific
SKU:10003-50UL
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About the Target
This antibody is suited for researchers who want to evaluate Integrin alpha-3 (ITGA3) and relate it to cell-state biology. Integrin alpha-3 is a matrix-interaction protein often examined in migration and morphogenesis models. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol ITGA3.
Research Context
Comparative experiments can separate expression differences from changes in adhesion structure abundance. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- co-variation with cytoskeletal and scaffold partners
- focal adhesion versus diffuse membrane distribution
- remodeling after changes in substrate or mechanical stress
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
If your study spans multiple model systems, it can help to define a shared reference condition for Integrin alpha-3 so cross-sample contrasts stay meaningful.
When interpreting Integrin alpha-3, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the regular format variant when your project demands Integrin alpha-3 (ITGA3) readouts that respect preparation constraints.
- Targets:
- ITGA3
- Research Area:
- Developmental Biology • Immunology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of human integrin alpha-3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P26006
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C