Indometacin Sodium

1 1

Selleck Chemicals

S5010-25MG

€95,00 EUR
€95,00 EUR
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Indometacin Sodium is an inhibitor of COX and COX-1 and related targets used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses.

By inhibiting COX and COX-1 and related targets, Indometacin Sodium can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving COX and COX-1 and related targets
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Indometacin Sodium is appropriate when a defined chemical perturbant is needed to connect COX and COX-1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
COX • COX-1 • COX-2
Target Class:
Enzyme
Pathways:
NF-kB Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
74252-25-8
Molecular Weight:
433.82
Formula:
C₁₉H₂₁ClNNaO₇
SMILES:
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)[O-].O.O.O.[Na+]
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.