IMM-H007

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Selleck Chemicals

S4460-5MG

€254,00 EUR
€254,00 EUR
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IMM-H007 is an activator of AMPK and NF-kB and related targets used in studies of PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in autophagy, cancer, and cell signaling models.

By activating AMPK and NF-kB and related targets, IMM-H007 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving AMPK and NF-kB and related targets
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling and related signaling programs
  • Gain-of-function pathway-activation studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, IMM-H007 is appropriate when a defined chemical perturbant is needed to connect AMPK and NF-kB and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
AMPK • NF-kB • JNK
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • MAPK / ERK Signaling • NF-kB Signaling
Research Area:
Autophagy • Cancer • Cell Signaling • Immunology
CAS No.:
1221412-23-2
Molecular Weight:
485.45
Formula:
C₂₂H₂₃N₅O₈
SMILES:
CC(=O)OCC1OC(C(OC(C)=O)C1OC(C)=O)[N]2C=NC3=C(NC4=CC=CC(=C4)O)N=CN=C23
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.