ILDR2 (Angulin-3) Antibody - FFPE Validated

Protein Function

Plan your comparisons around ILDR2 and use this antibody to explore state-dependent differences. ILDR2 is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.

In some datasets and protocols, it is referenced by the gene symbol Angulin-3.

Experimental Applications

Shifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Time course design can be decisive when regulation is transient or compartment dependent.

Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.

Common experimental questions that benefit from target tracking include:

• changes in complex assembly with scaffold or adaptor proteins
• comparative profiling across cell states or perturbations
• subcellular redistribution at contact sites versus cytoplasm

Workflow Perspective

This fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so ILDR2 patterns can be compared across experiments without guesswork.

Integrate the fixed-section version into your design so ILDR2 signals can be interpreted alongside matched controls.