IAXO-102

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Selleck Chemicals

S0002-2MG

€144,00 EUR
€144,00 EUR
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IAXO-102 is an antagonist of TLR and NF-kB used in studies of MAPK / ERK Signaling and NF-kB Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and inflammatory transcriptional control and stress-responsive survival signaling in immunology and inflammation models.

By blocking TLR and NF-kB, IAXO-102 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TLR and NF-kB
  • Pathway perturbation studies connected to MAPK / ERK Signaling and NF-kB Signaling and related signaling programs
  • Receptor-blockade and ligand-competition studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, IAXO-102 is appropriate when a defined chemical perturbant is needed to connect TLR and NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TLR • NF-kB
Target Class:
Immunomodulator
Pathways:
MAPK / ERK Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
1115270-63-7
Molecular Weight:
585.94
Formula:
C₃₅H₇₁NO₅
SMILES:
CCCCCCCCCCCCCCOC1C(C(OC(C1OCCCCCCCCCCCCCC)OC)CN)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.