GW4869

1 1

Selleck Chemicals

S7609-5MG

€144,00 EUR
€144,00 EUR
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GW4869 is an inhibitor of Phospholipases and Lipases used in studies of Apoptosis and Metabolic Signaling. It is especially relevant in apoptosis, cancer, and inflammation models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By inhibiting Phospholipases and Lipases, GW4869 can be used to examine caspase-associated cell-death signaling and survival decisions and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Phospholipases and Lipases
  • Pathway perturbation studies connected to Apoptosis and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, GW4869 is appropriate when a defined chemical perturbant is needed to connect Phospholipases and Lipases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Phospholipases • Lipases
Target Class:
Enzyme
Pathways:
Apoptosis • Metabolic Signaling
Research Area:
Apoptosis • Cancer • Inflammation • Metabolism
CAS No.:
6823-69-4
Molecular Weight:
577.5
Formula:
C₃₀H₂₈N₆O₂·2HCl·ₓH₂O
SMILES:
C1CN=C(N1)C2=CC=C(C=C2)NC(=O)C=CC3=CC=C(C=C3)C=CC(=O)NC4=CC=C(C=C4)C5=NCCN5.Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.