GSK2982772
Selleck Chemicals
SKU:S8484-2MG
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GSK2982772 is an inhibitor of RIPK used in studies of Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell signaling models.
By inhibiting RIPK, GSK2982772 can be used to examine caspase-associated cell-death signaling and survival decisions. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving RIPK
- Pathway perturbation studies connected to Apoptosis
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, GSK2982772 is appropriate when a defined chemical perturbant is needed to connect RIPK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- RIPK
- Target Class:
- Kinase
- Pathways:
- Apoptosis
- Research Area:
- Apoptosis • Cancer • Cell Signaling • Immunology
- CAS No.:
- 1622848-92-3
- Molecular Weight:
- 377.40
- Formula:
- C₂₀H₁₉N₅O₃
- SMILES:
- CN1C2=CC=CC=C2OCC(C1=O)NC(=O)C3=NNC(=N3)CC4=CC=CC=C4
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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