GSK2033

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Selleck Chemicals

E1142-5MG

€144,00 EUR
€144,00 EUR
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GSK2033 is an antagonist of LXR used in studies of Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

By blocking LXR, GSK2033 can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving LXR
  • Pathway perturbation studies connected to Metabolic Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, GSK2033 is appropriate when a defined chemical perturbant is needed to connect LXR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
LXR
Target Class:
Nuclear Receptor
Pathways:
Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
1221277-90-2
Molecular Weight:
591.66
Formula:
C₂₉H₂₈F₃NO₅S₂
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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