GABRA2 Antibody
BiCell Scientific
SKU:15102-50UL
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About the Target
Plan your comparisons around GABRA2 and use this antibody to analyze state-dependent differences. GABRA2 is a membrane protein linked to solute movement and gradient maintenance. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
Tracking GABRA2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Time course design can be decisive when regulation is transient or compartment dependent. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Consider these angles when interpreting target-level changes:
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. Include controls that separate true target shifts from matrix or preparation effects.
When interpreting GABRA2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
If your study spans multiple model systems, it can help to define a shared reference condition for GABRA2 so cross-sample contrasts stay meaningful.
Integrate the regular format version into your design so GABRA2 signals can be interpreted alongside matched controls.
- Targets:
- GABRA2
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of human GABRA2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P47869
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C