FL-411

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Selleck Chemicals

S1027-5MG

€350,00 EUR
€350,00 EUR
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FL-411 is an inhibitor of BET used in studies of PI3K-Akt-mTOR Signaling and Autophagy and related signaling programs. It is especially relevant in autophagy, cancer, and epigenetics models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation.

By inhibiting BET, FL-411 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BET
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Autophagy and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, FL-411 is appropriate when a defined chemical perturbant is needed to connect BET with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BET
Target Class:
Epigenetic Regulator
Pathways:
PI3K-Akt-mTOR Signaling • Autophagy • Epigenetic Regulation
Research Area:
Autophagy • Cancer • Epigenetics • Metabolism
CAS No.:
2118944-88-8
Molecular Weight:
341.43
Formula:
C₁₈H₁₉N₃O₂S
SMILES:
CC1=CC(=CC(=C1O)C)C2=NC3=C(C4=C(S3)CN(CC4)C)C(=O)N2
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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