FDL169

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Selleck Chemicals

SKU:S8795-5MG

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FDL169 is a modulator of CFTR used in studies of ion-channel pharmacology. It is especially relevant in cell signaling models, where defined compound exposure can be linked to ion conductance, membrane potential, and electrophysiological responses. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By modulating CFTR, FDL169 can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CFTR
  • Context-dependent response profiling and mechanism comparison
  • Electrophysiology, ion-flux, and membrane-potential studies
  • Phenotypic profiling in cell signaling models

Overall, FDL169 is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CFTR
Target Class:
Ion Channel
Research Area:
Cell Signaling
CAS No.:
1628416-28-3
Molecular Weight:
486.49
SMILES:
CCOC1=CC2=C(C=C1)C(=NN(C2=O)CC(=O)N(C)C3=CC4=C(C=C3)N=C(O4)C)C5=CC(=CC=C5)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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