Evobrutinib

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Selleck Chemicals

SKU:S8777-5MG

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Evobrutinib is an inhibitor of BTK used in studies of Immune Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses in cancer, cell signaling, and immunology models.

By inhibiting BTK, Evobrutinib can be used to examine cytokine-mediated signaling and inflammatory effector responses. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BTK
  • Pathway perturbation studies connected to Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Evobrutinib is appropriate when a defined chemical perturbant is needed to connect BTK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BTK
Target Class:
Kinase
Pathways:
Immune Signaling
Research Area:
Cancer • Cell Signaling • Immunology
CAS No.:
1415823-73-2
Molecular Weight:
429.51
Formula:
C₂₅H₂₇N₅O₂
SMILES:
C=CC(=O)N1CCC(CC1)CNC2=NC=NC(=C2C3=CC=C(C=C3)OC4=CC=CC=C4)N
InChIKey:
QUIWHXQETADMGN-UHFFFAOYSA-N
PubChem:
724217
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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