Ethacrynate Sodium
Selleck Chemicals
SKU:S5847-5MG
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Ethacrynate Sodium is an inhibitor of Proton Pump used in studies of transporter biology. It is especially relevant in cardiovascular and metabolism models, where defined compound exposure can be linked to substrate uptake, efflux, and membrane-transport control.
By inhibiting Proton Pump, Ethacrynate Sodium can be used to examine substrate uptake, efflux, and membrane-transport control. This target class is commonly examined through transport, uptake/efflux, and permeability assays, together with downstream-response mapping. In cardiovascular and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Proton Pump
- Concentration-response inhibition and target-dependence studies
- Transport, uptake/efflux, and permeability assays
- Phenotypic profiling in cardiovascular and metabolism models
Overall, Ethacrynate Sodium is appropriate when a defined chemical perturbant is needed to connect Proton Pump with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Proton Pump
- Target Class:
- Transporter
- Research Area:
- Cardiovascular • Metabolism
- CAS No.:
- 6500-81-8
- Molecular Weight:
- 325.12
- Formula:
- C₁₃H₁₁Cl₂NaO₄
- SMILES:
- CCC(=C)C(=O)C1=C(C(=C(C=C1)OCC(=O)[O-])Cl)Cl.[Na+]
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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