(±)-Equol

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Selleck Chemicals

SKU:S6601-5MG

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(±)-Equol is an agonist of Estrogen/Progesterone Receptors used in studies of Hormone Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation in endocrinology models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By activating Estrogen/Progesterone Receptors, (±)-Equol can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Estrogen/Progesterone Receptors
  • Pathway perturbation studies connected to Hormone Signaling
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, (±)-Equol is appropriate when a defined chemical perturbant is needed to connect Estrogen/Progesterone Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Estrogen/Progesterone Receptors
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Endocrinology
CAS No.:
94105-90-5
Molecular Weight:
242.27
Formula:
C₁₅H₁₄O₃
SMILES:
C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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