EPZ004777

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Selleck Chemicals

S7353-5MG

€193,00 EUR
€193,00 EUR
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EPZ004777 is an inhibitor of Histone Methyltransferases and Transferases used in studies of Apoptosis and Epigenetic Regulation and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation in apoptosis, cancer, and epigenetics models.

By inhibiting Histone Methyltransferases and Transferases, EPZ004777 can be used to examine caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Histone Methyltransferases and Transferases
  • Pathway perturbation studies connected to Apoptosis and Epigenetic Regulation and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, EPZ004777 is appropriate when a defined chemical perturbant is needed to connect Histone Methyltransferases and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Histone Methyltransferases • Transferases
Target Class:
Epigenetic Regulator
Pathways:
Apoptosis • Epigenetic Regulation • Metabolic Signaling
Research Area:
Apoptosis • Cancer • Epigenetics • Metabolism
CAS No.:
1338466-77-5
Molecular Weight:
539.67
Formula:
C₂₈H₄₁N₇O₄
SMILES:
CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=CC4=C(N=CN=C43)N)O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.