ENaC beta (Scnn1b) Antibody
BiCell Scientific
SKU:20342-50UL
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Biological Background
Designed to help you assess ENaC beta (Scnn1b), this antibody supports studies where protein context matters. ENaC beta is a membrane protein linked to solute movement and gradient maintenance. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol Scnn1b.
Use in the Laboratory
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.
To keep datasets interpretable, labs often document:
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
Version Notes
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.
If your study spans multiple model systems, it can help to define a shared reference condition for ENaC beta so cross-sample contrasts stay meaningful.
For challenging targets, pairing ENaC beta measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
As you refine hypotheses around ENaC beta (Scnn1b), the regular format format helps keep conclusions tied to preparation context.
- Targets:
- SCNN1B
- Research Area:
- Metabolism • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal cytoplasmic region of mouse ENaC beta subunit protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P51168
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 88.9% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C