Ellagic acid
Selleck Chemicals
SKU:S1327-50MG
Couldn't load pickup availability

Ellagic acid is an inhibitor of Topoisomerase used in studies of DNA Damage Response and Oxidative Stress Response. It is especially relevant in cancer, dna damage / repair, and oxidative stress models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and redox signaling, ROS handling, and antioxidant defenses.
By inhibiting Topoisomerase, Ellagic acid can be used to examine checkpoint activation, DNA repair, and genome-stability control and redox signaling, ROS handling, and antioxidant defenses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and oxidative stress models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Topoisomerase
- Pathway perturbation studies connected to DNA Damage Response and Oxidative Stress Response
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, Ellagic acid is appropriate when a defined chemical perturbant is needed to connect Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and oxidative stress models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Topoisomerase
- Target Class:
- Enzyme
- Pathways:
- DNA Damage Response • Oxidative Stress Response
- Research Area:
- Cancer • DNA Damage / Repair • Oxidative Stress
- CAS No.:
- 476-66-4
- Molecular Weight:
- 302.19
- Formula:
- C₁₄H₆O₈
- SMILES:
- C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O
- InChIKey:
- AFSDNFLWKVMVRB-UHFFFAOYSA-N
- PubChem:
- 5281855
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.
The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.