Elimusertib (BAY-1895344)hydrochloride

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Selleck Chemicals

S8666-2MG

€144,00 EUR
€144,00 EUR
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Elimusertib (BAY-1895344)hydrochloride is an inhibitor of ATR and ATM used in studies of DNA Damage Response. It is especially relevant in cancer, cell signaling, and dna damage / repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.

By inhibiting ATR and ATM, Elimusertib (BAY-1895344)hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ATR and ATM
  • Pathway perturbation studies connected to DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Elimusertib (BAY-1895344)hydrochloride is appropriate when a defined chemical perturbant is needed to connect ATR and ATM with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ATR • ATM
Target Class:
Kinase
Pathways:
DNA Damage Response
Research Area:
Cancer • Cell Signaling • DNA Damage / Repair
Molecular Weight:
411.89
Formula:
C₂₀H₂₂ClN₇O
SMILES:
CC1COCCN1C2=NC3=C(C=CN=C3C4=CC=NN4)C(=C2)C5=CC=NN5C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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