Doxycycline
Selleck Chemicals
SKU:S5159-25MG
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Doxycycline is an inhibitor of MMP used in studies of protease biology. In practice, this places the compound in experiments that measure proteolytic processing and cleavage-dependent signaling in cancer, inflammation, and infectious disease models.
By inhibiting MMP, Doxycycline can be used to examine proteolytic processing and cleavage-dependent signaling. This target class is commonly examined through protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping. In cancer, inflammation, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving MMP
- Concentration-response inhibition and target-dependence studies
- Protease-activity, cleavage, and substrate-processing assays
- Phenotypic profiling in cancer, inflammation, and infectious disease models
Overall, Doxycycline is appropriate when a defined chemical perturbant is needed to connect MMP with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, inflammation, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- MMP
- Target Class:
- Protease
- Research Area:
- Cancer • Inflammation • Infectious Disease
- CAS No.:
- 564-25-0
- Molecular Weight:
- 444.43
- Formula:
- C₂₂H₂₄N₂O₈
- SMILES:
- CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
- InChIKey:
- JBIWCJUYHHGXTC-AKNGSSGZSA-N
- PubChem:
- 54671203
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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