DNMT3B Antibody
BiCell Scientific
SKU:82024-50UL
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About the Target
Designed to help you investigate DNMT3B, this antibody supports studies where protein context matters. DNMT3B is a molecular target often examined to connect phenotype changes with underlying protein regulation. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Following DNMT3B across perturbations can help separate expression effects from compartment shifts.
Research Context
Comparative experiments across cell states can uncover patterns that single-condition measurements miss. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- cross-sample normalization strategies
- subcellular compartment mapping
- baseline versus stimulated condition comparisons
Variant Considerations
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so DNMT3B patterns can be compared across experiments without guesswork.
For challenging targets, pairing DNMT3B measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for DNMT3B so cross-sample contrasts stay meaningful.
As you refine hypotheses around DNMT3B, the regular format format helps keep conclusions tied to preparation context.
- Targets:
- DNMT3B
- Research Area:
- Epigenetics
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of mouse DNMT3B protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9UBC3
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 50% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C