DNMT3A Antibody - Western Blot Validated
BiCell Scientific
SKU:82023-WB-50UL
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About the Target
This antibody is suited for researchers who want to assess DNMT3A and relate it to cell-state biology. DNMT3A is a protein of interest for mapping abundance changes across conditions and cell states. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking DNMT3A can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Context
Comparative experiments across cell states can uncover patterns that single-condition measurements miss. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- baseline versus stimulated condition comparisons
- cross-sample normalization strategies
- subcellular compartment mapping
Variant Considerations
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing DNMT3A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for DNMT3A so cross-sample contrasts stay meaningful.
For challenging targets, pairing DNMT3A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the denaturing-format variant when your project demands DNMT3A readouts that respect preparation constraints.
- Targets:
- DNMT3A
- Research Area:
- Epigenetics
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the N-terminal region of human DNMT3A protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y6K1
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C