Dibutyryl cAMP (db cAMP/Bucladesine)sodium

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Selleck Chemicals

S7858-100MG

€173,00 EUR
€173,00 EUR
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Dibutyryl cAMP (db cAMP/Bucladesine)sodium is an activator of PKA and PDE used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cancer, cardiovascular, and cell signaling models.

By activating PKA and PDE, Dibutyryl cAMP (db cAMP/Bucladesine)sodium can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cardiovascular, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PKA and PDE
  • Pathway perturbation studies connected to GPCR Signaling
  • Gain-of-function pathway-activation studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Dibutyryl cAMP (db cAMP/Bucladesine)sodium is appropriate when a defined chemical perturbant is needed to connect PKA and PDE with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PKA • PDE
Target Class:
Kinase
Pathways:
GPCR Signaling
Research Area:
Cancer • Cardiovascular • Cell Signaling • Neuroscience
CAS No.:
16980-89-5
Molecular Weight:
491.37
Formula:
C₁₈H₂₃N₅NaO₈P
SMILES:
CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+]
PubChem:
6539774
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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