Dexrazoxane

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Selleck Chemicals

S5651-25MG

€144,00 EUR
€144,00 EUR
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Dexrazoxane is a substrate of Topoisomerase used in studies of DNA Damage Response. It is especially relevant in cancer and dna damage / repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.

As a substrate linked to Topoisomerase, Dexrazoxane can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Topoisomerase
  • Pathway perturbation studies connected to DNA Damage Response
  • Kinetic, turnover, and substrate-competition experiments
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Dexrazoxane is appropriate when a defined chemical perturbant is needed to connect Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Topoisomerase
Target Class:
Enzyme
Pathways:
DNA Damage Response
Research Area:
Cancer • DNA Damage / Repair
CAS No.:
24584-09-6
Molecular Weight:
268.27
Formula:
C₁₁H₁₆N₄O₄
SMILES:
CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
InChIKey:
BMKDZUISNHGIBY-ZETCQYMHSA-N
PubChem:
71384
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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