Dexamethasone

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Selleck Chemicals

SKU:S1322-50MG

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Dexamethasone is an agonist of Interleukins and Glucocorticoid Receptor used in studies of JAK-STAT Signaling and Immune Signaling and related signaling programs. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses in autophagy, endocrinology, and immunology models.

By activating Interleukins and Glucocorticoid Receptor, Dexamethasone can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In autophagy, endocrinology, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Interleukins and Glucocorticoid Receptor
  • Pathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling and related signaling programs
  • Agonist-response and downstream signaling studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, Dexamethasone is appropriate when a defined chemical perturbant is needed to connect Interleukins and Glucocorticoid Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, endocrinology, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Interleukins • Glucocorticoid Receptor
Target Class:
Immunomodulator
Pathways:
JAK-STAT Signaling • Immune Signaling • Autophagy
Research Area:
Autophagy • Endocrinology • Immunology • Inflammation
CAS No.:
50-02-2
Molecular Weight:
392.46
Formula:
C₂₂H₂₉FO₅
SMILES:
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
InChIKey:
UREBDLICKHMUKA-CXSFZGCWSA-N
PubChem:
5743
Storage Temperature:
4°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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