Desmocollin-3 (DSC3) (Extracellular) (Human) Antibody - Western Blot Validated
BiCell Scientific
SKU:00189H-WB-50UL
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Protein Function
Use this antibody to investigate Desmocollin-3 Extracellular when mapping complex behavior and signaling context. Desmocollin-3 Extracellular is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol DSC3.
Experimental Applications
Junction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.
Common experimental questions that benefit from target tracking include:
- co-localization patterns with cytoskeletal elements
- subcellular redistribution at contact sites versus cytoplasm
- comparative profiling across cell states or perturbations
Workflow Perspective
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
If your study spans multiple model systems, it can help to define a shared reference condition for Desmocollin-3 Extracellular so cross-sample contrasts stay meaningful.
Choose the denaturing-format format to study Desmocollin-3 Extracellular in a way that stays anchored to pathway logic.
- Targets:
- DSC3
- Research Area:
- Developmental Biology
- Application:
- WB
- Reactivity:
- Human
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the N-terminal extracellular region of human Desmocollin-3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q14574
- Homology:
- Synthetic peptide sequence shows 76.5% homology to rodent sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C