CXCR5 (CD185) Antibody
BiCell Scientific
SKU:64155-50UL
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Scientific Overview
Use this antibody to examine CXCR5 when mapping complex behavior and signaling context. CXCR5 is a receptor-linked protein that can influence cell communication and downstream signaling. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol CD185.
Research Relevance
Immune markers are often interpreted alongside a panel of complementary targets to improve population resolution. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- panel-based interpretation with additional lineage markers
- activation-dependent changes across stimulation conditions
- comparisons across differentiation or polarization states
Application-Specific Context
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CXCR5 patterns can be compared across experiments without guesswork.
Choose the regular format format to study CXCR5 in a way that stays anchored to pathway logic.
- Targets:
- CXCR5
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal cytoplasmic region of mouse CXCR5 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P32302
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C