CXCR1 (CD128 or CD181 or IL8RA) Antibody - Western Blot Validated

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BiCell Scientific

SKU:64151-WB-50UL

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Blocking Peptide
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About the Target

This antibody enables you to investigate CXCR1 (CD128) with a direct, biology-first readout. CXCR1 is an immune-related target that can reflect differentiation, activation, or trafficking behavior. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol CD128.

Research Context

Experimental perturbations such as cytokine exposure can reshape marker abundance and localization patterns. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Consider these angles when interpreting target-level changes:

  • panel-based interpretation with additional lineage markers
  • assessment of surface versus internalized pools
  • activation-dependent changes across stimulation conditions
  • comparisons across differentiation or polarization states

Variant Considerations

When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CXCR1 patterns can be compared across experiments without guesswork.

When interpreting CXCR1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

Select the denaturing-format version to keep CXCR1 (CD128) interpretation aligned with your workflow goals.

Targets:
CXCR1
Research Area:
Cell Signaling • Developmental Biology • Immunology • Inflammation
Application:
WB
Reactivity:
Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the N-terminal extracellular region of mouse CXCR1 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P25024
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 25% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C