Claudin-10 (CLDN10) Antibody
BiCell Scientific
SKU:00210-50UL
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Scientific Overview
This antibody enables you to investigate Claudin-10 with a direct, biology-first readout. Claudin-10 is a contact-site protein that shapes barrier properties and signaling at the cell surface. Focus on trends across conditions rather than single-point snapshots.
Tracking Claudin-10 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
In cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.
When building a narrative around the target, it helps to track:
- comparative profiling across cell states or perturbations
- changes in complex assembly with scaffold or adaptor proteins
- co-localization patterns with cytoskeletal elements
- subcellular redistribution at contact sites versus cytoplasm
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
If your study spans multiple model systems, it can help to define a shared reference condition for Claudin-10 so cross-sample contrasts stay meaningful.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Claudin-10 patterns can be compared across experiments without guesswork.
With a clear focus on Claudin-10, this regular format option fits streamlined studies and fast iteration.
- Targets:
- CLDN10
- Research Area:
- Developmental Biology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of human Claudin-10 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P78369
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C