CHRNB2 (nAChRB2) Antibody
BiCell Scientific
SKU:15192-50UL
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About the Target
This antibody enables you to evaluate CHRNB2 (nAChRB2) with a direct, biology-first readout. CHRNB2 is a membrane-embedded regulator of ionic or osmotic balance in cells. Look for shifts in distribution that track with phenotype changes.
In some datasets and protocols, it is referenced by the gene symbol nAChRB2.
Research Context
Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Pair measurements with orthogonal readouts when interpretation is sensitive to context. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Consider these angles when interpreting target-level changes:
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
- patterns consistent with apical or basolateral sorting
- relative abundance across engineered constructs
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting CHRNB2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
For challenging targets, pairing CHRNB2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
With a clear focus on CHRNB2 (nAChRB2), this regular format option fits streamlined studies and fast iteration.
- Targets:
- CHRNB2
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of human CHRNB2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P17787
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C