CHRNB2 (nAChRB2) Antibody

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BiCell Scientific

SKU:15192-50UL

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Size
Blocking Peptide
Quantity
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About the Target

This antibody enables you to evaluate CHRNB2 (nAChRB2) with a direct, biology-first readout. CHRNB2 is a membrane-embedded regulator of ionic or osmotic balance in cells. Look for shifts in distribution that track with phenotype changes.

In some datasets and protocols, it is referenced by the gene symbol nAChRB2.

Research Context

Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Pair measurements with orthogonal readouts when interpretation is sensitive to context. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

Consider these angles when interpreting target-level changes:

  • surface versus intracellular pool distribution
  • stimulus-dependent trafficking and turnover
  • patterns consistent with apical or basolateral sorting
  • relative abundance across engineered constructs

Variant Considerations

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

When interpreting CHRNB2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

For challenging targets, pairing CHRNB2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

With a clear focus on CHRNB2 (nAChRB2), this regular format option fits streamlined studies and fast iteration.

Targets:
CHRNB2
Research Area:
Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (13-aa) derived from the N-terminal extracellular region of human CHRNB2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P17787
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C