CHRNA6 Antibody
BiCell Scientific
SKU:15186-50UL
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Biological Background
To connect mechanism with measurement, this antibody lets you evaluate CHRNA6 in pathway-driven studies. CHRNA6 is a channel or transporter associated with regulated flux across cellular membranes. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Following CHRNA6 across perturbations can help separate expression effects from compartment shifts.
Use in the Laboratory
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.
To keep datasets interpretable, labs often document:
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
Version Notes
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.
For challenging targets, pairing CHRNA6 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
When interpreting CHRNA6, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the regular format version to relate CHRNA6 behavior to upstream cues and downstream consequences.
- Targets:
- CHRNA6
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse CHRNA6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q15825
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C