CHRNA3 (NACHRA3) Antibody

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BiCell Scientific

SKU:15183-50UL

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Blocking Peptide
Quantity
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Scientific Overview

This antibody enables you to examine CHRNA3 (NACHRA3) with a direct, biology-first readout. CHRNA3 is a membrane protein linked to solute movement and gradient maintenance. Focus on trends across conditions rather than single-point snapshots.

Following CHRNA3 across perturbations can help separate expression effects from compartment shifts.

Research Relevance

Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

When building a narrative around the target, it helps to track:

  • patterns consistent with apical or basolateral sorting
  • surface versus intracellular pool distribution
  • stimulus-dependent trafficking and turnover
  • relative abundance across engineered constructs

Application-Specific Context

For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

For challenging targets, pairing CHRNA3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

With a clear focus on CHRNA3 (NACHRA3), this regular format option fits streamlined studies and fast iteration.

Targets:
CHRNA3
Research Area:
Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (14-aa) derived from the N-terminal extracellular region of mouse CHRNA3 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P32297
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 78.6% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C