CHRNA3 (NACHRA3) Antibody
BiCell Scientific
SKU:15183-50UL
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Scientific Overview
This antibody enables you to examine CHRNA3 (NACHRA3) with a direct, biology-first readout. CHRNA3 is a membrane protein linked to solute movement and gradient maintenance. Focus on trends across conditions rather than single-point snapshots.
Following CHRNA3 across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
Application-Specific Context
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
For challenging targets, pairing CHRNA3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
With a clear focus on CHRNA3 (NACHRA3), this regular format option fits streamlined studies and fast iteration.
- Targets:
- CHRNA3
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the N-terminal extracellular region of mouse CHRNA3 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P32297
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 78.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C