Cerdulatinib (PRT062070)hydrochloride

1 1

Selleck Chemicals

S7634-10MG

€144,00 EUR
€144,00 EUR
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Cerdulatinib (PRT062070)hydrochloride is an inhibitor of JAK and SYK and related targets used in studies of JAK-STAT Signaling and Immune Signaling. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses in cancer, cell signaling, and immunology models.

By inhibiting JAK and SYK and related targets, Cerdulatinib (PRT062070)hydrochloride can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving JAK and SYK and related targets
  • Pathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Cerdulatinib (PRT062070)hydrochloride is appropriate when a defined chemical perturbant is needed to connect JAK and SYK and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
JAK • SYK • JAK1 • JAK2
Target Class:
Kinase
Pathways:
JAK-STAT Signaling • Immune Signaling
Research Area:
Cancer • Cell Signaling • Immunology • Inflammation
CAS No.:
1369761-01-2
Molecular Weight:
482
Formula:
C₂₀H₂₈ClN₇O₃S
SMILES:
CCS(=O)(=O)N1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4CC4)C(=O)N.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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