CEP120 (CCDC100) Antibody

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BiCell Scientific

SKU:01085-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

Use this antibody to examine CEP120 when mapping complex behavior and signaling context. CEP120 is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

In some datasets and protocols, it is referenced by the gene symbol CCDC100.

Research Relevance

Because cilia length and assembly can vary, experimental design often benefits from standardized culture timing. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.

When building a narrative around the target, it helps to track:

  • co-occurrence with intraflagellar transport markers
  • changes in cilia incidence or apparent length in perturbation studies
  • cell-cycle linked differences in localization

Application-Specific Context

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.

When interpreting CEP120, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

Use the regular format version to relate CEP120 behavior to upstream cues and downstream consequences.

Targets:
CEP120
Research Area:
Cell Cycle • Developmental Biology
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the C-terminal region of mouse CEP120 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q8N960
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 75% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C