Centrin-1 Antibody - Western Blot Validated
BiCell Scientific
SKU:01061-WB-50UL
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About the Target
Use this antibody to examine Centrin-1 when mapping complex behavior and signaling context. Centrin-1 is a microtubule-organizing element often evaluated in cell-cycle and cilia studies. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Following Centrin-1 across perturbations can help separate expression effects from compartment shifts.
Research Context
Disruption of intraflagellar transport or basal body function can produce distinct localization signatures. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- changes in cilia incidence or apparent length in perturbation studies
- co-occurrence with intraflagellar transport markers
- cell-cycle linked differences in localization
Variant Considerations
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting Centrin-1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
For challenging targets, pairing Centrin-1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Choose the denaturing-format format to study Centrin-1 in a way that stays anchored to pathway logic.
- Targets:
- CETN1
- Research Area:
- Cell Cycle • Developmental Biology
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal region of mouse Centrin-1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q12798
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.4% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C