CCR5 (CD195) Antibody - Western Blot Validated

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BiCell Scientific

SKU:64135-WB-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

Use this antibody to characterize CCR5 in your model system. CCR5 is an immune-related target that can reflect differentiation, activation, or trafficking behavior. Look for shifts in distribution that track with phenotype changes.

Tracking CCR5 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.

Research Relevance

Comparisons across tissues or culture conditions can highlight activation-dependent shifts in expression. Pair measurements with orthogonal readouts when interpretation is sensitive to context.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.

When building a narrative around the target, it helps to track:

  • panel-based interpretation with additional lineage markers
  • activation-dependent changes across stimulation conditions
  • assessment of surface versus internalized pools
  • comparisons across differentiation or polarization states

Application-Specific Context

For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CCR5 patterns can be compared across experiments without guesswork.

If your study spans multiple model systems, it can help to define a shared reference condition for CCR5 so cross-sample contrasts stay meaningful.

With a clear focus on CCR5, this denaturing-format option fits streamlined studies and fast iteration.

Targets:
CCR5
Research Area:
Cell Signaling • Developmental Biology • Immunology • Inflammation
Application:
WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse CCR5 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
P51681
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 80% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C