CCR4 (CD194) Antibody - FFPE Validated
BiCell Scientific
SKU:64134-FFPE-50UL
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Scientific Overview
Bring CCR4 into view to evaluate changes across conditions. CCR4 is a receptor-linked protein that can influence cell communication and downstream signaling. Look for shifts in distribution that track with phenotype changes.
Monitoring CCR4 alongside context markers can improve interpretation when phenotypes are subtle.
Research Relevance
Because expression can be context dependent, matched controls and gating strategies help avoid over-interpretation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- assessment of surface versus internalized pools
- panel-based interpretation with additional lineage markers
- comparisons across differentiation or polarization states
- activation-dependent changes across stimulation conditions
Application-Specific Context
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CCR4 patterns can be compared across experiments without guesswork.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CCR4 patterns can be compared across experiments without guesswork.
Select the fixed-section version to keep CCR4 interpretation aligned with your workflow goals.
- Targets:
- CCR4
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal cytoplasmic region of mouse CCR4 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P51679
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 78.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C