Caveolin-2 Antibody

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Selleck Chemicals

SKU:F1431-20UL

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About the Target

CAVEOLIN2 is a target of interest in many antibody-based workflows. The caveolin gene family in vertebrates includes caveolin-1 (cav-1), caveolin-2 (cav-2), and caveolin-3 (cav-3), which are integral membrane proteins of 20-24 kD that serve as markers of caveolae. Cav-2 a 20 kD protein, identified from adipocyte-derived caveolar membranes, exists in three isoforms: cav-2α, cav-2β, and cav-2γ. Depending on the literature source, CAVEOLIN2 may also be discussed as Caveolin-2.

Reported cellular context includes cell membrane, cytoplasm, golgi apparatus, and membrane, which can matter when signal is compared across treatments or changing cell states. Following CAVEOLIN2 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.

Research Context

CAVEOLIN2 is commonly interpreted in the context of metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cytoplasm, and golgi apparatus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.

Consider these angles when interpreting target-level changes:

  • apparent redistribution between cell membrane, cytoplasm, and golgi apparatus across matched conditions
  • responses linked to nutrient status, mitochondrial state, or metabolic rewiring
  • co-patterning with orthogonal markers and control conditions that clarify pathway state
  • time-matched comparisons so changes reflect biology rather than handling or sampling drift

Variant Considerations

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CAVEOLIN2. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.

Standardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CAVEOLIN2 reflect biology rather than handling. When interpreting CAVEOLIN2, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.

For multi-run studies, a shared reference condition can keep CAVEOLIN2 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.

Targets:
CAVEOLIN2
Research Area:
Metabolism
Application:
IF • IP • WB
Reactivity:
Human • Monkey
Specificity:
Caveolin-2 Antibody [L20J2] recognizes endogenous levels of total caveolin-2 protein. Based on amino acid sequence, the antibody is not expected to cross-react with caveolin-1 or caveolin-3.
Host:
Rabbit
Clonality:
Monoclonal
Clone:
L20J2
UniProt:
P51636
Storage Buffer:
PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.