Caspase-2 (CASP2 or NEDD2) Antibody
BiCell Scientific
SKU:10302-50UL
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Protein Function
When you need to investigate Caspase-2 with attention to cellular organization, this antibody provides a focused option. Caspase-2 is a signaling node often evaluated by abundance, localization, and modification-dependent states. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CASP2.
Experimental Applications
Signaling targets are typically assessed across time courses to capture transient activation windows. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.
Common experimental questions that benefit from target tracking include:
- localization shifts between cytoplasm, membrane, and nucleus
- time-resolved changes following stimulation or inhibition
- condition-to-condition comparisons with matched controls
Workflow Perspective
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
If your study spans multiple model systems, it can help to define a shared reference condition for Caspase-2 so cross-sample contrasts stay meaningful.
If your study spans multiple model systems, it can help to define a shared reference condition for Caspase-2 so cross-sample contrasts stay meaningful.
Use the regular format variant when your project demands Caspase-2 readouts that respect preparation constraints.
- Targets:
- CASP2
- Research Area:
- Apoptosis • Cell Signaling
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of human Caspase-2 protein (p13 subunit)
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P42575
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C