Canagliflozin hemihydrate

1 1

Selleck Chemicals

S5901-10MG

€95,00 EUR
€95,00 EUR
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Canagliflozin hemihydrate is an inhibitor of SGLT used in studies of GPCR Signaling and Metabolic Signaling. It is especially relevant in endocrinology and metabolism models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By inhibiting SGLT, Canagliflozin hemihydrate can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SGLT
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Canagliflozin hemihydrate is appropriate when a defined chemical perturbant is needed to connect SGLT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SGLT
Target Class:
Transporter
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
928672-86-0
Molecular Weight:
907.05
Formula:
C₄₈H₅₂F₂O₁₁S₂
SMILES:
CC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F.CC1=C(C=C(C=C1)C2C(C(C(C(O2)CO)O)O)O)CC3=CC=C(S3)C4=CC=C(C=C4)F.O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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