CACNA1S (Cav1.1) Antibody
BiCell Scientific
SKU:11041-50UL
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Protein Function
To connect mechanism with measurement, this antibody lets you analyze CACNA1S in pathway-driven studies. CACNA1S is a membrane-embedded regulator of ionic or osmotic balance in cells. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Monitoring CACNA1S alongside context markers can improve interpretation when phenotypes are subtle.
Experimental Applications
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.
Common experimental questions that benefit from target tracking include:
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
For challenging targets, pairing CACNA1S measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
When interpreting CACNA1S, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The regular format option supports mechanistic reading of CACNA1S when interactions and context are the focus.
- Targets:
- CACNA1S
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of mouse Cav1.1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q13698
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.8% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C