CACNA1A (Cav2.1) Antibody
BiCell Scientific
SKU:11044-50UL
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About the Target
When you need to assess CACNA1A with attention to cellular organization, this antibody provides a focused option. CACNA1A is a channel or transporter associated with regulated flux across cellular membranes. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Following CACNA1A across perturbations can help separate expression effects from compartment shifts.
Research Context
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
Variant Considerations
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing CACNA1A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so CACNA1A patterns can be compared across experiments without guesswork.
Use the regular format variant when your project demands CACNA1A readouts that respect preparation constraints.
- Targets:
- CACNA1A
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the N-terminal region of mouse Cav2.1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O00555
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 86.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C