Bleomycin hydrochloride
Selleck Chemicals
SKU:E4789-5MG
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Bleomycin hydrochloride is an inhibitor of DNA/RNA Synthesis used in studies of DNA Damage Response and Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and dna damage / repair models.
By inhibiting DNA/RNA Synthesis, Bleomycin hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving DNA/RNA Synthesis
- Pathway perturbation studies connected to DNA Damage Response and Apoptosis
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, Bleomycin hydrochloride is appropriate when a defined chemical perturbant is needed to connect DNA/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- DNA/RNA Synthesis
- Target Class:
- Enzyme
- Pathways:
- DNA Damage Response • Apoptosis
- Research Area:
- Apoptosis • Cancer • DNA Damage / Repair • Infectious Disease
- CAS No.:
- 67763-87-5
- Molecular Weight:
- 1452.01
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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