BIX-01294 Trihydrochloride

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Selleck Chemicals

S8006-10MG

€144,00 EUR
€144,00 EUR
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BIX-01294 Trihydrochloride is an inhibitor of Histone Methyltransferases and Transferases used in studies of Autophagy and Epigenetic Regulation and related signaling programs. It is especially relevant in autophagy, cancer, and epigenetics models, where defined compound exposure can be linked to autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation.

By inhibiting Histone Methyltransferases and Transferases, BIX-01294 Trihydrochloride can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Histone Methyltransferases and Transferases
  • Pathway perturbation studies connected to Autophagy and Epigenetic Regulation and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, BIX-01294 Trihydrochloride is appropriate when a defined chemical perturbant is needed to connect Histone Methyltransferases and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Histone Methyltransferases • Transferases
Target Class:
Epigenetic Regulator
Pathways:
Autophagy • Epigenetic Regulation • Metabolic Signaling
Research Area:
Autophagy • Cancer • Epigenetics • Metabolism
CAS No.:
1392399-03-9
Molecular Weight:
600.02
Formula:
C₂₈H₃₈N₆O₂·3HCl
SMILES:
CN1CCCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)NC4CCN(CC4)CC5=CC=CC=C5)OC)OC.Cl.Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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