Birabresib (OTX015)

1 1

Selleck Chemicals

S7360-2MG

€144,00 EUR
€144,00 EUR
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Birabresib (OTX015) is an inhibitor of BET used in studies of Epigenetic Regulation. In practice, this places the compound in experiments that measure chromatin-state control, histone modification, and transcriptional regulation in cancer and epigenetics models.

By inhibiting BET, Birabresib (OTX015) can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BET
  • Pathway perturbation studies connected to Epigenetic Regulation
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, Birabresib (OTX015) is appropriate when a defined chemical perturbant is needed to connect BET with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BET
Target Class:
Epigenetic Regulator
Pathways:
Epigenetic Regulation
Research Area:
Cancer • Epigenetics
CAS No.:
202590-98-5
Molecular Weight:
491.99
Formula:
C₂₅H₂₂ClN₅O₂S
SMILES:
CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C
InChIKey:
GNMUEVRJHCWKTO-UHFFFAOYSA-N
PubChem:
9936746
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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