β-thujaplicin

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Selleck Chemicals

SKU:S4771-25MG

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β-thujaplicin is an inhibitor of DNA Methyltransferases and Transferases used in studies of Oxidative Stress Response and Epigenetic Regulation and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to redox signaling, ROS handling, and antioxidant defenses and chromatin-state control, histone modification, and transcriptional regulation in cancer, epigenetics, and infectious disease models.

By inhibiting DNA Methyltransferases and Transferases, β-thujaplicin can be used to examine redox signaling, ROS handling, and antioxidant defenses and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, epigenetics, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving DNA Methyltransferases and Transferases
  • Pathway perturbation studies connected to Oxidative Stress Response and Epigenetic Regulation and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, β-thujaplicin is appropriate when a defined chemical perturbant is needed to connect DNA Methyltransferases and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, epigenetics, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
DNA Methyltransferases • Transferases
Target Class:
Epigenetic Regulator
Pathways:
Oxidative Stress Response • Epigenetic Regulation • Metabolic Signaling
Research Area:
Cancer • Epigenetics • Infectious Disease • Metabolism
CAS No.:
499-44-5
Molecular Weight:
164.20
Formula:
C₁₀H₁₂O₂
SMILES:
CC(C)C1=CC(=O)C(=CC=C1)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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